Abstract: What have these algorithms based on immune theory offered for engineering application? Are there differences between them? On the background of these questions，three classic immune algorithms，B-cell algorithm，clonal selection algorithm and Opt-aiNET，are taken for examples and are compared in terms of the following two criterions：the quality of optimal solution obtained and the number of evaluation to objective function with three classic engineering problems.The differences between them are given and reasons are also analyzed.

Key words: immune theory, clonal selection algorithm, B-cell algorithm, Opt-aiNET algorithm

摘要： 基于免疫机理的算法为工程应用带来了什么、有何差异。基于这个背景，选择B-cell 算法、克隆选择算法和Opt-aiNET算法这三个免疫算法为代表，针对三类经典工程优化问题，以解质量和评价数作为评价标准，详尽地比较了它们，并给出了它们之间差异原因的分析和评价。

关键词: 免疫理论, 克隆选择算法, B-cell算法, Opt-aiNET算法