Advances in Classification of Lung Adenocarcinoma Subtypes

doi:10.3778/j.issn.1002-8331.2210-0116

Abstract

Abstract: There are many different types of lung adenocarcinoma, and each has its own characteristics. Accurate classification of lung adenocarcinoma is an important basis for clinical diagnosis and treatment. Classification of lung adenocarcinoma subtypes from histopathology, imaging, genomics and other aspects has always been one of the hot issues in clinical research. Especially in recent years, the development of machine learning and deep learning technology has provided new methods and ideas for the classification of lung adenocarcinoma. In this paper, the research progress of the classification techniques of lung adenocarcinoma is described in detail, and the application progress of the classification techniques of various subtypes is systematically evaluated. This paper summarizes the advantages and disadvantages of various classification technologies, the difficulty of traditional classification methods and the algorithm complexity of common machine learning and deep learning technology models, analyzes the relevant problems in current research, and looks forward to the future research direction.

Key words: lung adenocarcinoma, classification technique, computed tomography（CT） imaging, pathological tissue image, machine learning, deep learning

摘要： 肺腺癌存在多种不同类型，各有表征，准确对其分类是临床诊断和治疗的重要依据。从肺腺癌组织病理学、影像学、基因组学等多个方面进行肺腺癌亚型分类研究一直是临床研究的热点问题之一。特别是近年来机器学习和深度学习技术的发展为肺腺癌分类研究提供了新的方法和思路。详细阐述了当前肺腺癌分类技术的研究进展，对各种亚型分类技术应用进展进行了系统的评价。总结了各类分类技术的优缺点、传统分类方法的难易程度和常用的机器学习、深度学习技术模型的算法复杂度，分析了当前研究的相关问题，并对未来的研究方向进行了展望。

关键词: 肺腺癌, 分类技术, 计算机断层扫描（CT）影像, 病理组织图像, 机器学习, 深度学习

LIU Mingchuan, ZHANG Kuixing, JIANG Mei, ZHANG Xiaoli, LI Liping. Advances in Classification of Lung Adenocarcinoma Subtypes[J]. Computer Engineering and Applications, 2023, 59(17): 67-79.

刘茗传, 张魁星, 江梅, 张晓丽, 李丽萍. 肺腺癌亚型分类技术研究进展[J]. 计算机工程与应用, 2023, 59(17): 67-79.

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