Computer Engineering and Applications ›› 2007, Vol. 43 ›› Issue (28): 61-64.
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XIE Jing-yu,XIE Shen-quan
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谢靖宇,谢深泉
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Abstract: The algorithm MSA is presented in this paper,which improved the way to compute D(k) and k-optimal Spectral Alignment of SA algorithm and took into account simultaneous analysis of N-terminal and C-terminal ions.The experiment result data shows that efficiently improves the capability of identifying proteins containing mutations or post-translational modifications.
Key words: protein, Post-translational Modification, mutation, MSA algorithm
摘要: 提出的MSA(Modified Spectral Alignment)算法,改进了SA(Spectral Alignment)算法中D(k)和k-最佳Spectral Alignment的求解方式,并在算法中引入“双端考虑”。实验结果数据表明,MSA算法有效地提高了鉴定含突变或翻译后修饰的蛋白质的能力。
关键词: 蛋白质, 翻译后修饰, 突变, MSA算法
XIE Jing-yu,XIE Shen-quan. Algorithm identifying mutations and post-translational modification of protein[J]. Computer Engineering and Applications, 2007, 43(28): 61-64.
谢靖宇,谢深泉. 一种鉴定蛋白质突变和翻译后修饰的算法[J]. 计算机工程与应用, 2007, 43(28): 61-64.
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