Computer Engineering and Applications ›› 2020, Vol. 56 ›› Issue (11): 192-199.DOI: 10.3778/j.issn.1002-8331.1904-0388

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Exudates Detection in Fundus Image Based on Fuzzy C-Means Clustering and Edge-Aware Model

LIU Juntao, WANG Sujuan, LIN Xiaoming, LIU Zuoshi, TAN Jianhui, SONG Dan   

  1. 1.College of Mechanical and Electrical Engineering, Jiangxi University of Science and Technology, Ganzhou, Jiangxi  341000, China
    2.Guangdong Shunde Innovation Design Institute, Shunde, Guangdong 528311, China
    3.College of Automation, Guangdong University of Technology, Guangzhou 510006, China
    4.College of Information Science and Engineering , Guilin University of Technology, Guilin, Guangxi 541006, China
  • Online:2020-06-01 Published:2020-06-01



  1. 1.江西理工大学 机电工程学院,江西 赣州 341000
    2.广东顺德创新设计研究院,广东 顺德 528311
    3.广东工业大学 自动化学院,广州 510006
    4.桂林理工大学 信息科学与工程学院,广西 桂林 541006


Exudates in the fundus image is one of the early symptoms of Diabetic Retinopathy(DR), a method for detecting exudates by combining Fuzzy C-Means(FCM) clustering and edge-aware model is proposed. In order to ensure the accuracy and efficiency of post-detection, the fundus image is firstly subjected to preprocessing such as enhanced contrast and equalized brightness, and then the exudates candidate region is segmented by FCM clustering, after that the candidate is determined by the edge-aware model based on the judgment of neighborhood grayscale difference. Finally, the real exudates area is obtained by removing the optic disc area. The approach is evaluated on the public fundus image data set, the sensitivity of the algorithm is 86.65%, the specificity is 94.79%, the positive predictive value is 95.14%, and the accuracy is 92.09%. The results show that the method can effectively realize the automatic detection of the fundus exudates.

Key words: exudates detection, image preprocessing, fuzzy C-means clustering, edge-aware model


眼底图像中渗出物是构成糖尿病视网膜病变(Diabetic Retinopathy,DR)的早期症状之一,提出一种结合模糊C-均值(Fuzzy C-Means,FCM)聚类和边缘感知模型的方法实现对渗出物的检测。为保证后期检测精度和效率,对眼底图像进行增强对比度和均衡亮度等预处理操作,用FCM聚类分割出渗出物候选区域,利用基于判断邻域灰度差异的边缘感知模型对候选区域进行筛选,通过移除视盘区域,从而得到真实的渗出物区域。在公开的数据集上进行实验,算法的灵敏度为86.65%,特异性为94.79%,阳性预测值为95.14%,准确度为92.09%。结果表明,该方法能够有效实现对眼底渗出物的自动检测。

关键词: 渗出物检测, 图像预处理, 模糊C均值聚类, 边缘感知模型