Improved population migration algorithm for prediction of protein folding

Computer Engineering and Applications ›› 2008, Vol. 44 ›› Issue (2): 83-85.

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Improved population migration algorithm for prediction of protein folding

WANG Jian-yong¹,CHEN Hua-feng¹,MO Zhong-xi²,NIU Xiao-hui¹,LI Zhi¹

1.College of Science，Huazhong Agricultural University，Wuhan 430070，China
2.School of Mathematics and Statistics，Wuhan University，Wuhan 430072，China

Received:1900-01-01 Revised:1900-01-01 Online:2008-01-11 Published:2008-01-11
Contact: WANG Jian-yong

一种改进人口迁移算法在蛋白质折叠模拟中的应用

王建勇¹,陈华锋¹,莫忠息²,牛晓辉¹,李治¹

1.华中农业大学理学院，武汉 430070
2.武汉大学数学与统计学院，武汉 430072

通讯作者: 王建勇

Abstract

Abstract: A simulation test of PMA is done in the off-lattice model.The numerical results enunciate that the population migration algorithm has strong global searching ability and stability.To the thought of PMA，this paper improves the population migration algorithm.The improved algorithm to solve 2-dimension off-lattice model obtains better results of the prediction.

Key words: protein folding, off-lattice model, population migration algorithm, improved population migration algorithm

摘要： PMA（Population Migration Algorithm）算法已在蛋白质非晶格模型中做了模拟测试，结果表明具有较强的全局搜索能力和稳定性。针对PMA算法的思想，提出了对算法的一种改进。使用该改进算法求解蛋白质折叠构形预测的二维非晶格模型取得了较好的计算结果。

关键词: 蛋白质折叠, 非晶格模型, 人口迁移算法, 改进人口迁移算法

WANG Jian-yong¹,CHEN Hua-feng¹,MO Zhong-xi²,NIU Xiao-hui¹,LI Zhi¹. Improved population migration algorithm for prediction of protein folding[J]. Computer Engineering and Applications, 2008, 44(2): 83-85.

王建勇¹,陈华锋¹,莫忠息²,牛晓辉¹,李治¹. 一种改进人口迁移算法在蛋白质折叠模拟中的应用[J]. 计算机工程与应用, 2008, 44(2): 83-85.

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Improved population migration algorithm for prediction of protein folding

一种改进人口迁移算法在蛋白质折叠模拟中的应用

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