Computer Engineering and Applications ›› 2021, Vol. 57 ›› Issue (15): 1-8.DOI: 10.3778/j.issn.1002-8331.2101-0281

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Research Progress of Medical Image Registration Technology Based on Deep Learning

GUO Yanfen, CUI Zhe, YANG Zhipeng, PENG Jing, HU Jinrong   

  1. 1.Chengdu Institute of Computer Application, Chinese Academy of Sciences, Chengdu 610041, China
    2.University of Chinese Academy of Sciences, Beijing 100049, China
    3.School of Computer Science, Chengdu University of Information Technology, Chengdu 610225, China
  • Online:2021-08-01 Published:2021-07-26



  1. 1.中国科学院 成都计算机应用研究所,成都 610041
    2.中国科学院大学,北京 100049
    3.成都信息工程大学 计算机学院,成都 610225


Medical image registration technology has a wide range of application values for lesion detection, clinical diagnosis, surgical planning, and efficacy evaluation. This paper systematically summarizes the registration algorithm based on deep learning, and analyzes the advantages and limitations of various methods from deep iteration, full supervision, weak supervision to unsupervised learning. In general, unsupervised learning has become the mainstream direction of medical image registration research, because it does not rely on golden standards and uses an end-to-end network to save time. Meanwhile, compared with other methods, unsupervised learning can achieve higher accuracy and spends shorter time. However, medical image registration methods based on unsupervised learning also face some research difficulties and challenges in terms of interpretability, cross-modal diversity, and repeatable scalability in the field of medical images, which points out the research direction for achieving more accurate medical image registration methods in the future.

Key words: medical image registration, deep learning, unsupervised learning, multi-modal medical image



关键词: 医学图像配准, 深度学习, 无监督学习, 多模态医学图像