Novel method of gene features extraction in cancer recognition

doi:10.3778/j.issn.1002-8331.2010.30.067

Computer Engineering and Applications ›› 2010, Vol. 46 ›› Issue (30): 237-240.DOI: 10.3778/j.issn.1002-8331.2010.30.067

• 工程与应用 • Previous Articles Next Articles

Novel method of gene features extraction in cancer recognition

LU Xin-guo，PENG Xiang-hua，LI Dan，ZHOU Peng-jie，CHEN Dong

School of Computer and Communication，Hunan University，Changsha 410082，China

Received:2009-02-23 Revised:2009-04-14 Online:2010-10-21 Published:2010-10-21
Contact: LU Xin-guo

在癌症识别中一种新颖的基因特征抽取算法

卢新国，彭湘华，李丹，周鹏杰，陈东

湖南大学计算机与通信学院，长沙 410082

通讯作者: 卢新国

Abstract

Abstract: Using the cancerogenic factor’s local correlation to a type of cancer，a novel method of gene features extraction is proposed.Using gene features transformation，the cancerogenic factors are extracted to different cancers and a relative space is built to the cancer，then the gene features are extracted for cancers with them.The cancer pattern is proved to can be recognized.The experiment is explored in the Leukemia dataset and Colon dataset，the results show that AML/ALL and to Tumor Colon Tissue（TCT）/normal Colon Tissue（NCT） are recognized effectively.

Key words: gene expression profile, gene feature extraction, cancer recognition

摘要： 针对癌症样本类型存在的局部相关性，提出了一种新颖的基因特征抽取算法。利用基因表达谱中基因表达数据的空间映射，提取不同类型癌症的致癌因子，并构建癌症组的关联空间，在关联空间之上抽取分类基因特征。理论证明可以有效识别癌症模式，并在急性白血病数据集上进行实验，结果表明利用抽取的分类基因特征可以有效识别AML/ALL。

关键词: 基因表达谱, 基因特征抽取, 癌症分类

CLC Number:

LU Xin-guo，PENG Xiang-hua，LI Dan，ZHOU Peng-jie，CHEN Dong. Novel method of gene features extraction in cancer recognition[J]. Computer Engineering and Applications, 2010, 46(30): 237-240.

卢新国，彭湘华，李丹，周鹏杰，陈东. 在癌症识别中一种新颖的基因特征抽取算法[J]. 计算机工程与应用, 2010, 46(30): 237-240.

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Novel method of gene features extraction in cancer recognition

在癌症识别中一种新颖的基因特征抽取算法

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