Abstract: The application restrictions of DV-Hop are broken through starting from its model.According to the principle of total least squares，the location problem of sensors is studied in wireless sensor network when the anchor node location information exists errors，and more general results are obtained.In the simulation scene with size 100×100，100 sensor nodes，communication radius 30m，Gaussian noise variance 1 and the ratio of anchor node less than 8%，the simulation demonstrates that this approach can improve the location accuracy of WSN significantly.Its average location accuracy increases by 20%~30% than the original method.The two methods tend to have the same accuracy when the ratio of anchor nodes is greater than 8%.