Abstract: The image obtained by some sensors will be degraded unavoidably due to some inner and outer reasons of imaging system.In order to obtain high resolution image，the image super-resolution technology has been developed rapidly.A novel blind Poisson MAP algorithm is established，which may synchronously estimate high-resolution image and blur function containing shift factors.Compared with fundamental blind Poisson MAP algorithm，this algorithm can suppress oscillatory artifacts effectively and improve the definition greatly and increase peak SNR about 7 dB.