Abstract: The conventional FCM don’t take into account the spatial information of image and can get the unexpected results of segmentation when dealing with some image contaminated by noise.Inspired by the MRF model，considering the pixel and its neighbor，an improved model is presented to fuzzy C-means algorithm using neighborhood information.The proposed algorithm can reasonably use the spatial information of image and improve the accuracy of segmentation.The results of experiments show that the proposed algorithm can provide powerful image segmentation than many segmentation algorithms.