关键词: 分泌蛋白, 哈斯矩阵, 模糊K近邻算法, Jackknife测试

Abstract: It is important to identify whether an uncharacterized protein sequence is a secretory proteins or not because secretory proteins are composed with signal peptides which are crucial tool in finding new drugs or reprogramming cells for gene therapy.Based on the assumption that proteins belonging to a same class must bear some sort of similar texture on the protein Hasse matrix images，geometric invariant moment factors derived from the image are used as the pseudo amino acid components to formulate the protein samples for statistical prediction.The success rates obtained on a previously constructed benchmark dataset are quite promising.

Key words: secretory proteins, Hasse matrix, fuzzy K nearest neighbor algorithm, Jackknife cross-validation test