Abstract: A novel audio information hiding algorithm based on the audio sample dots inversion is proposed.Based on extensive experiments，we find that the similarity coefficient of the original audio’s waveform and the attacked audio’s waveform is high when the frame length is appropriate.And it has little influence on the human hearing after inversing the audio sample dots in a period of time.Based on those features，at first we divide the host audio into several frames，then inverse the audio sample dots to embed secret information.We extract the secret information by judging the polarity of the similarity coefficient，and the resynchronization is designed to increase the correct rate.Experimental results show that the watermarked audio has good imperceptibility and is robust against different kinds of attacks，such as noise adding，low-pass filtering，resampling，echo，Mp3 compression，especially it can resist the attacks of the DA/AD conversions and desynchronization.