Abstract: A new level set PDE based on the simplified Mumford-Shah model for image segmentation is proposed by Chan and Vese（CV model） and Geodesic Active Contours（GAC） mode.In order to overcome limitation of both models，the evolution function is constructed based on local edge information and the global region information and then novel level set model is presented.Experimental results of synthesis image and infrared image suggest that our model is more efficient and accurate in its segmentation operations.