Abstract: This paper presents an effective multi-sensor image registration method combining high-pass energy transformation and feature point matching.First，the SUSAN algorithm is used to obtain the corners of the two images.And then，the matching procedure is realized with two stages：For coarse matching，the normalized local cross-correlation based on high-pass energy image is defined as similarity measurement to obtain the original correspondence；For precise matching，the robust RANSAC algorithm is applied to discard the incorrectly matched corner pairs and get the registrationt parameters.The validity and exactness have been shown by the experimental results.