Abstract: According to the requirements of the order-picking problem of the fixed shelve in the automated warehouse,a kind of rapid and efficient hybrid genetic algorithm is analyzed and designed.A compensatory algorithm is presented for the construction of the initial population and a cross arithmetic operators and converse mutation arithmetic operators enlightened by greedy algorithm are for the operation.The ability of local searching of general genetic algorithm is prominently improved.The simulation indicates that this method can acquire good results,satisfying the demands of the work as to efficiency and optimization results.