Abstract: A parallel multiplication algorithm based on sticker model of DNA computing is proposed in this article.The multiplication of two numbers is converted into a series of replacement additions of the multiplier according to the multiplicand.The multiplicand and multiplier are encoded in the same DNA strand，and the product is computed by operations of combination，separation，set，and clear.Because the structure of the output strands is exactly similar to that of the input strand，the result can be further reused without any changes.The algorithm can not only be utilized in multiplication of integers，but also easily extended in multiplication of decimals.The salient advantage of the algorithm is that the time for computing a lot of groups of multiplication is same as that for computing a group of multiplication on condition that the number of the　factor is same as the number of the latter.The algorithm makes the best of the potential parallelism of DNA computing.