Abstract: After the introduction of the self-similarity of complex network，it expatiates on the basic principle and method about self-similarity exponential and its computational method box covering algorithm，with the empirical investigation for 4 different kinds of human biological networks.The results suggest that metabolic networks are self-similarity，whether including current and small metabolite or not，while other biological networks are almost not self-similarity.

Key words: complex network, metabolic network, protein-protein interaction network, signal transduction network, disease network, self-similarity

摘要： 介绍了复杂网络自相似性的基本概念，阐述了自相似指数及其计算方法盒覆盖算法的基本原理和方法，并对四种不同类型的人类生物网络进行了实证分析。结果表明，无论是否考虑流通代谢物和小分子代谢物，新陈代谢网络都是自相似的，但是其他的生物网络大多不是自相似的。

关键词: 复杂网络, 代谢网络, 蛋白交互网络, 信号转导网络, 疾病网络, 自相似