Abstract: The present distributed clustering algorithms are generally designed for the uniform deployment WSN，and are not applied to the non-uniform deployment WSN.Load balancing and lower power consumption have become a major challenge of the non-uniform deployment WSN.For the non-uniform deployment WSN，a distributed Clustering Algorithm based on Regional Density（RDCA） is proposed.Firstly，the node tests the node density of which region the node is in.Then based on the regional density，the node adjusts its communication coverage and balances the load of every cluster.The simulation shows that in the non-uniform deployment WSN，compared with LEACH and HEED，this algorithm performs better at load balancing，and effectively improves the stability of the network cycle after clustering.